Uses
Danazol is used to treat a number of different medical problems. These include:
Endometriosis.
Fibrocystic breast disease (cysts in the breasts).
Hereditary angioedema (swelling of the different parts of the body, such as abdomen or stomach, arms, legs, throat, skin, or sexual organs
Dosage
The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.
For oral dosage form (capsules):
For treatment of mild endometriosis:
Adults—At first, 200 to 400 milligrams (mg), divided in two doses, for at least 3 to 6 months and up to 9 months. Your doctor may adjust your dose as needed and tolerated.
Children—Use and dose must be determined by your doctor.
For treatment of moderate to severe endometriosis:
Adults—At first, 800 milligrams (mg) per day, divided in two doses, for at least 3 to 6 months and up to 9 months. Your doctor may adjust your dose as needed and tolerated.
Children—Use and dose must be determined by your doctor.
For treatment of fibrocystic breast disease:
Adults—100 to 400 milligrams (mg) per day, divided in two doses. Your doctor may adjust your dose as needed and tolerated.
Children—Use and dose must be determined by your doctor.
For prevention of hereditary angioedema:
Adults—At first, 200 milligrams (mg) two or three times a day. Your doctor may adjust your dose as needed and depending upon your condition.
Children—Use and dose must be determined by your doctor.
Warnings and Precautions
In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered:
Allergies
Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.
Pediatric
Appropriate studies have not been performed on the relationship of age to the effects of danazol in the pediatric population. Safety and efficacy have not been established.
Geriatric
Although appropriate studies on the relationship of age to the effects of danazol have not been performed in the geriatric population, no geriatric-specific problems have been documented to date.
Breastfeeding
There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.
Using this medicine while you are pregnant can harm your unborn baby. If you are a woman who can bear children, your doctor may give you a pregnancy test before you start using this medicine to make sure you are not pregnant. Your birth control pills may not work as well while you are using this medicine. You must use an effective form of birth control (e.g., a condom, a diaphragm, spermicide) to keep from getting pregnant. If you think you have become pregnant while using the medicine, tell your doctor right away.
Using this medicine may cause irregular monthly periods or absence of menstrual period. If your regular monthly period does not begin within 60 to 90 days after you stop taking this medicine, check with your doctor right away.
Check with your doctor right away if you are a female and have a larger clitoris, deepening of your voice, or unusual hair growth after taking danazol. Your doctor may advise you to stop taking the medicine so these side effects do not get worse.
Stop using this medicine and check with your doctor if you have the following symptoms while taking this medicine: blurred vision; change in the ability to see colors, especially blue or yellow; headache; nausea; or vomiting.
